Diagnosing C3 Glomerulopathy

How is C3G diagnosed?

  • Your physician will perform a number of tests in order to establish a diagnosis. These may include:-

    • Full blood count – this is to look at the level of substances such as platelets and haemoglobin in your blood.

    • Urea & Electrolytesthis assesses your kidney function.

    • Complement studies – to measure the levels of complement proteins C3 & C4 in your blood and to look for the presence of autoantibodies to complement proteins.

    • Genetic testing – to see if you carry any of the known genetic faults associated with C3G.

    • Urinalysis – looks for evidence of blood and protein in your urine that can indicate kidney damage.

    • Ultrasound – a non-invasive scan that provides a general outline of the size and shape of your kidneys.

    • Biopsy – a small piece of kidney tissue is removed and looked at under a microscope. This provides a more accurate picture of what may be causing the damage to the kidney.