Patients receiving eculizumab must be vaccinated against meningococcal infection using the vaccines ACWY and Bexsero. As part of the monitoring of serological response, we recommend annual testing of ACWY titres. NB Due to the nature of the assay, B-titres cannot be tested whilst patients are receiving eculizumab. Our specialist aHUS nurses will usually be in touch to confirm the timing of these titres. Samples for testing should be requested using the following form, requesting measurement of ACWY titres. These tests are paid for by NHS England as part of the follow-up of patients receiving eculizumab within the National aHUS Service.
Download forms for requesting Meningococcal titres here